The Nobel Prize for Medicine includes the names of British and American scientists
The Nobel Prize for Medicine includes the names of British and American scientists | Scientists from the United States and the UK have announced the Nobel Prize for Medicine in 2019 for understanding and adjusting the oxygen levels of cells.
The discovery was announced at the Nobel Prize for Medicine at Sir Peter Rut Cliff of Oxford University, William Calvin of Harvard University, and Greg Sminza of Johns Hopkins University.
The research work of the three will help to develop new ways of treating anemia and cancer. “We have known for centuries the importance of oxygen, but do not know how the cells adapt to oxygen levels,” the Swedish Academy of Scientists said in their statement.
The cash prize of 90 million Norwegian kroner will be distributed among three scientists.
The oxygen levels in the body change, such as exercise, height, or an injury that results in a lower level and the cells themselves change accordingly much faster. Understanding oxygen plays a key role in the immune system and can result in the formation of red blood cells or the repair of arteries.
The discovery of these researchers suggests that drugs that can give the impression of oxygen depletion can be an effective way to control anemia.
Similarly, cancer messengers who control the formation and development of new blood vessels will also help prevent cancer in place of medicines.
In their work, these researchers discovered that a decrease in oxygen levels increases the level of the hormone erythropoietin or EPO, and that is because the protein combination modulates HIFDNA behavior.
Further research in this regard has revealed that when oxygen levels return to normal, cells continue to produce HIFs so that another protein can destroy VHL. But when oxygen levels are low, VHL does not rely on HIF, which in turn modulates DNA behavior.
Last year, Madison’s Nobel Prize was awarded to American and Japanese scientists who discovered a revolutionary approach to cancer treatment.
Similarly, in 2017, US scientists who discovered the biological clock-controlling molecular mechanism were awarded the world’s largest drug median.
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